Castroneves, who has three career Indianapolis 500 wins, crashed on Lap 146 and finished 27th on Sunday.
She was in very good spirits early in the race, when she started on the inside of Row 3 and was running near the top 10. While the cause of the wreck remains undetermined, Chip Ganassi Racing's Ed Jones suffered a similar incident just laps before without coming into contact with another auto.
Just before the singing of the national anthem, with the crowd as quiet as it would be all day, one fan screamed from the grandstands, "Let's go Danica!"
"Please, Roger, let me go back", Castroneves said after stepping out of his auto. Patrick announced months ago that she would retire after the Indy 500, the second half of the "Danica Double". He didn't get a great restart and was passed by Stefan Wilson and Jack Harvey. "As you got going, airflow over 200 is pretty good, it cooled everybody off".
The victory capped a flawless month of May for the man from Toowoomba as Power tuned up for the Indy 500 by notching up his 33rd career win with a victory in the Indianapolis Grand Prix run on the Speedway's road circuit.
Pole sitter Ed Carpenter finished second, Scott Dixon was third, and 2016 victor Alexander Rossi came from the back of the field to finish fourth. And once the Team Penske driver took the checkered flag, he and Liz let it all pour out.
Many drivers acknowledged passing was tough and handling was a problem, and it showed as seven crashes took out a slew of fan favorites and some of the most experienced drivers in the IndyCar Series.
"I was hoping to win", Rossi said. "But we had some good moments". We didn't qualify on the last row by pace, so I thought halfway when I was 18th or whatever that we could make good enough progress and the auto was fast and I could get to the front. She led 19 total and ultimately finished fourth. Power saw the two cars leave the track and was in utter disbelief. "I know all about that so no issues with what he did".
It's what you want with one of the biggest races in the world.
The 2016 Indianapolis 500 victor put on a show Sunday as he charged from 32nd to fourth in the NAPA Honda and made one of the most bodacious passes in recent history. I'm not going to look back.
Penske arrived in Indy with four fast Chevrolets, and the engine builder was determined to snap Honda's two-race Indy 500 winning streak.
She was examined at the Indianapolis Motor Speedway medical center and released.
Patrick left IndyCar and moved on to stock cars in 2012, but never won a race. It's a different mindset. You work hard at something, it comes to you.
"There is a hole and you go where there are no other cars".
Scott Dixon stretched his fuel to finish third and was followed by Alexander Rossi, who drove from 32nd to fourth and made some of the most spectacular moves in the race. "It was a great race".
I think he's gutted, as an understatement. What if I started 10th?
Penske also credited his strong lineup of 2014 series champion Power, 2016 champion Simon Pagenaud, reigning champion Josef Newgarden and three-time Indianapolis 500 victor Helio Castroneves.
The final box, the Indianapolis 500 box, remained bedeviling, too, however.
Will's victory at Indy was his 29th in the Verizon IndyCar Series.
Will Power couldn't contain his emotion after winning Sunday's Indianapolis 500. "I want to cry". "Some day he might drive for me!" He's a great champion. "I'll look forward. We have to be back next year". "But no doubt, we had a smile on our face".