Iranian Foreign Minister Javad Zarif sets off on Saturday for talks in China, Russia and Europe to see what can be salvaged.
JCPOA is an acronym for Joint Comprehensive Plan of Action, the agreement under which Iran agreed to cap uranium enrichment at below the level needed to make nuclear weapons, and to allow intrusive global inspections to ensure compliance, in return for the lifting of crippling financial sanctions.
Bolton also reiterated the administration's objection to the sunset provisions in the Iran deal, which President Donald Trump called "totally unacceptable".
The pair will be joined by German foreign minister Heiko Maas and European Union high representative Federica Mogherini for Tuesday's talks in Brussels, where they are also expected to meet Iranian foreign minister Mohammad Javad Zarif.
On Wednesday, the European Commission will meanwhile discuss the EU's 1990s-era blocking sanctions, Mogherini said.
White House national security adviser John Bolton said USA sanctions on European companies that maintain business dealings with Iran were "possible", while Secretary of State Mike Pompeo said he remained hopeful Washington and its allies could strike a new nuclear deal with Tehran.
French Foreign Minister Jean-Yves Le Drian said on Tuesday the Middle East was explosive and could be on the cusp of war.
Among them is the possible use of an EU "blocking regulation" which would, in essence, ban European companies from respecting American sanctions where those sanctions might damage EU interests, notably trade and the movement of capital.
Trump made his disdain for the Obama-era Iran deal well known from the start of his campaign for president in 2015.
The overall impact on oil supply and prices will depend on whether Iran stays in the deal and how severe the secondary sanctions are, the consulting company said in its analysis. The head of the Liberal faction in the European Parliament, Guy Verhofstadt, said that the new American leader was one of three - along with radical Islam and the Russian president Putin - threats that undermine the EU.
The United States threatened on Sunday to impose sanctions on European companies that do business with Iran, as the remaining participants in the Iran nuclear accord stiffened their resolve to keep that agreement operational.
The files - declared "authentic" by the USA government - document Iran's extensive work on nuclear weapons, including planned site tests, miniaturization of warheads and ballistic missile delivery vehicles.
Trump's interpretation of U.S. strategic interests has also led to withdrawal from major worldwide climate and trade accords, the paper said, noting that many have expressed concern about the lack of a visible plan.
Wang also noted that China regards Iran as an important partner within the Belt and Road initiative and would maintain bilateral cooperation with the Middle Eastern nation in various fields.