The release notes that "other initiatives that will aim to establish a footprint in the city" will also be scheduled.
Mr Manfred said: "The stadium infrastructure in this city gives Major League Baseball every opportunity to put on a first-class event".
The NFL has played regular-season games in London since 2007, holding 18 games at Wembley and three at Twickenham. "This is our most significant endeavor ever in Europe and we look forward to showcasing Major League Baseball in one of the world's great cities". "All the hard work has paid off", Khan said.
Khan said: "London is the sporting capital of the world".
"It's also the first time the Red Sox and Yankees have played one another outside of NY or Boston", added Henry, who also co-owns English Premier League side Liverpool. We could not be happier that Commissioner Manfred has been able to make this a reality. Two of the most recognizable teams are once again two of the best.
Major League Baseball is heading to London.
Red Sox owner John W. Henry said his team and the Yankees had been discussing the possibility of playing in London for several years. The venue will host Major League Baseball games in 2019 and 2020.
Now, Boston and NY will take their historic rivalry to the iconic Olympic Stadium (now known as London Stadium), which hosted the 2012 Summer Olympics and also is the home to the soccer club West Ham of the Premier League.