But he still has the possibility of becoming the Republican nominee for Senate on Tuesday, even though President Trump urged voters to support Rep. Evan Jenkins, R-W.Va. or Attorney General Patrick Morrisey.
Blankenship has made no bones about attacking other Republicans.
"Problem is, Don Blankenship, now running for Senate, can't win the General Election in your State", the president said.
Jenkins, a former Democrat, has repeatedly argued that Manchin missed a big chance to align himself with Trump on taxes and health care. He added that the "institution would be misinforming him because they usually do not desire me to function as from the U.S. Senate and market the President's schedule".
President Donald Trump has insisted his campaign did not collude with Russian Federation to help him win the election.
"Vote Rep. Jenkins or A.G. Morrisey!" the president also said in his tweet Monday.
As for West Virginia, the president's appeal to Republican voters comes at a crucial moment in the race.
The president had offered Moore his full-throated support in the days leading to the special election in the deep red Cotton State.
"Without an incumbent advantage in a year that seems to be favoring Democrats, that's a tough dynamic for Republicans", Askarinam said, "The question is whether Republicans believe that this district is still in the vein of Tiberi and Kasich".
The GOP views Manchin's seat as a prime pick-up opportunity to expand the party's narrow majority in the Senate. He has consistently voted against Senate Republicans' ObamaCare repeal or replace efforts and most recently their tax-cut bill that Trump signed in late-December 2017. President TrumpDonald John TrumpBaldwin spotlights mother's drug addiction, efforts to combat opioid abuse in ad Giuliani says he's "focused on the law more than the facts right now" Cambridge Analytica ordered to hand over data on U.S. voter MORE won West Virginia by more than 40 points in 2016.
The former chief executive of Massey Energy, Mr. Blankenship served a year in federal prison following being convicted of trying to violate Parliament security rules after the Upper Big Branch mining crisis this year that promised 29 lives.
Despite his past, the 68-year-old Blankenship and his anti-establishment message appear to be resonating with voters, in a state with a 5.4 percent jobless rate, the third-highest in the country.
"Swamp captain Mitch McConnell has created millions of jobs for China people", Blankenship said in the ad Politico first reported. Her father, entrepreneur and philanthropist James S.C. Chao, was born in China.
In recent weeks he has fought using a collection of incendiary advertisements targeting the group of Senator Mitch McConnell, the Senate majority leader and spouse of Transportation Secretary Elaine Chao.
Mr. McConnell, who is profoundly unpopular among Republican primary voters, has mainly sidestepped the attacks, but his allies also have continued to assail Mr. Blankenship.