The Blazers secured a narrow 111-110 victory over the visitors who were without Kawhi Leonard, Tony Parker, Danny Green and Rudy Gay.
Leonard hurt his shoulder during their 103-89 victory over the Phoenix Suns on Friday and it was originally diagnosed as a left shoulder strain.
A shorthanded San Antonio Spurs nearly came away with an impressive win on the road against the Portland Trail Blazers but suffered a loss in the final seconds as C.J. McCollum hit a game-winning shot.
"I don't think it will be a while", Popovich said in regards to Leonard's status, per ESPN. "It depends on how his shoulder goes".
Kawhi missed the first 27 games of the season recovering from a thigh injury that occurred in the offseason and has had minutes restrictions placed on him since coming back on top of missing another five games as the team has managed his return to full playing time. While they are unclear about how long his recovery will take, they are hopeful he can play Thursday. Popovich did not rule Leonard out for either game on Sunday, although Spurs guard Manu Ginobili told the media that, "We lose him for a few games, and we don't for how many, so it's been a tough season".
However, the Spurs are optimistic about his long-term outlook. He's played in 34 games this season after a serious injury last season.
He's played only eight games this season, resting for a game between each of his past seven appearances.
It certainly makes the Spurs' record all the more impressive having accomplished a 27-13 start mostly without their MVP-caliber star. Gasol is averaging almost 11 points and eight rebounds per game.